Wade H. Brown papers, Rockefeller Institute for Medical Research Scientific Staff (FA010) ca. 1911-1942

0.88 cubic feet (2 document cases)

File Plan

Former Classification: I 450 B815

Physical Characteristics and Technical Requirements

Materials requiring specialized equipment for access (film, audio, video, slides) may be closed to research dependent on availability of the applicable equipment

Brittle or damaged items, or materials otherwise in need of preservation care, may be closed to researchers at the discretion of the RAC Head of Archival Services/Head of Reference.

Scope and Contents

Bibliography, biographical material, correspondence, manuscripts, photographs, reprints. Includes material about the development of the drug Tryparsamide for chemotherapy of African sleeping sickness and syphilis. Correspondents include John Auer (1926) and Arthur S. Loevenhart (1914-1926).

Biographical / Historical

Wade Hampton Brown (1878-1942) was a research physician in pathology at The Rockefeller Institute for Medical Research, 1913-1942. He specialized in the study of the biology of syphilitic infections. His work in experimental chemotherapy of various trypanosomal and spirochetal infections affecting man and certain domestic animals resulted in the arsenical compound tryparsamide for the treatment of African sleeping sickness and in the therapy of general paresis. This was followed by a long series of studies on constitutional factors and physical environment in relation to disease, the inheritance of disease types and various genetic concepts.

Many of his publications were co-authored with Louise Pearce.

Member of: Association of American Physicians American Society of Pathologists and Bacteriologists American Society for Experimental Pathology American Society for Pharm. and Experimental Therapeutics Society for Experimental Biology and Medicine A.A.A.S. Sigma Xi Nu Sigma Nu

1878
Born October 18, Sparta, Georgia
1899
B.S., University of Nashville
1902-1903
Graduate student at the University of Chicago
1907
M.D., Johns Hopkins University
1907-1908
Instructor in pathology, University of Virginia
1908-1910
Instructor in pathology, University of Wisconsin
1910-1911
Assistant professor in pathology, University of Wisconsin
1911-1913
Professor in pathology, University of North Carolina
1913-1914
Associate in Pathology and Bacteriology, Rockefeller Institute for Medical Research(RIMR), New York, NY
1914-1922
Associate Member, RIMR
1922-1942
Member, RIMR (1935 transferred to Princeton Laboratories)
1942
Died August 4, Rice Lake, Wisconsin

Immediate Source of Acquisition

Gift of The Rockefeller University administration. Received September 1974.

Custodial History

The papers in Box 2 were found with various patent related documents that had been stored in the Welch Hall-Rockefeller University archives vault. Dr. Brown is the principal correspondent, and the papers have been arranged as part of his Institute file.

Processing Information

Processed by Carolyn Kopp, November 7, 1985.

Conditions Governing Access

Collection is open for scholarly research.

Conditions Governing Use

RAC users must abide by all applicable provisions of United States copyright law. Reproduction/duplication of archival items is routinely provided in accordance with “fair use”. If the RAC does not hold copyright for an archival collection, or items within a collection, it is the users’ responsibility to contact the copyright holder, or make a fair effort to do so, prior to publication.

Preferred Citation

Information regarding the Rockefeller Archive Center’s preferred elements and forms of citation can be found at http://www.rockarch.org/research/citations.php

Related Archival Materials

Official patent correspondence has been arranged with FA137 Rockefeller University records, Business Manager, Subject Files (Series 7)

Contents

Biographical material, photographs, memorial minute, bibliography, reports on development of scientific work

Box 1, Folder 1

Report of death, telegrams, posthumous letters, committee for completing work on constitution

Box 1, Folder 2

Administrative correspondence, 1911-1929

Box 1, Folder 3

Administrative correspondence, 1930-1942

Box 1, Folder 4

Collected Reprints
re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1914

Box 2, Folder 1

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1919

Box 2, Folder 2

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1920

Box 2, Folder 3

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1921

Box 2, Folder 4

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1922

Box 2, Folder 5

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1923 January-June

Box 2, Folder 6

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1923 September-December

Box 2, Folder 7

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1924 January-February

Box 2, Folder 8

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1924 March

Box 2, Folder 9

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1924 April-December

Box 2, Folder 10

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1925

Box 2, Folder 11

re: Tryparsamide work - Loevenhart, Arthur S. Correspondence, 1926

Box 2, Folder 12

re: Tryparsamide work - A.S. Loevenhart Mss. 16 pp.

Box 2, Folder 13

re: Tryparsamide work - "Statement as to the agreement entered into with Dr. Loevenhart for the Study of Tryparsamide", ca. 1924 January

Box 2, Folder 14

re: Tryparsamide work - re: C. Leake's paper in "Science"., 1925 Seotember 18

Box 2, Folder 15

re: Tryparsamide work - Copies of unused Mss re: Loevenhart statement in "Science".

Box 2, Folder 16

re: Tryparsamide work - "Science" issues 1925 18 September and 25 December, 1925

Box 2, Folder 17

re: Tryparsamide work - Auer, John, 1926

Box 2, Folder 18

re: Tryparsamide work - Chicago Medical Society Bulletin 8, 1923 December 15

Box 2, Folder 19

re: Tryparsamide work - Clipping, The Capitol Times (?), Madison, WI, 1926 January 5

Box 2, Folder 20